Abstract: In the Low Earth Orbit satellite network, the satellite runs fast, the operating cycle is short, and the inter-satellite link changes dynamically. In order to perceive the state of the inter-satellite link in time and select the correct route, a low-orbit satellite intelligent sensing routing algorithm based on Dendrite network is proposed. Through the visibility constraints between satellites to analyze the situation of inter-satellite link establishment, realize inter-satellite link situational awareness. By constructing training sets in real time, Dendrite Network was used to automatically adjust the weights of global satellite network links, and then optimize the traditional Dijkstra algorithm, realize the quality perception of inter-satellite links, and give intelligent routing decisions. The initial routing path is corrected in real time by periodically monitoring the satellite network topology. The simulation results show that the routing algorithm based on Dendrite Network has low complexity, and the path delay, delay jitter and the packet loss ratio are all lower than the traditional heuristic routing algorithm and Dijkstra routing algorithm.