Taking the catalytic oxidation of VOCs as the topic, 4654 papers were processed by Web of Science database, and the development tendency and research status of the topic were analyzed by the way of bibliometrics. The results show that VOCs catalytic oxidation has abundant research depth in the past 25 years, and the research prospect is admirable, the number of published papers shows an exponential growth trend. China is the country with the largest contribution of publications in the world, accounting for 34% of total research. The biggest producing institution and journal are University of Chinese Academy of Sciences (6.66%) and Applied Catalysis B-Environmental (11.68) respectively. Chemistry and Engineering are the most popular subjects. In addition, the hot words analysis in recent years shows that the most popular substance in the catalyst is Mn, while toluene is the most common substrate of VOCs in the experiment. At the same time, common catalyst substances and VOCs substrates are summarized in this paper, which reflects the current main research direction and provides guidance for future research.